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is a small Dutch company striving to enhance neurovascular monitoring by introducing innovative techniques within the Intensive Care Unit. Central to the Neuromon approach is the theory of arterial acceleration proposed by Dr. A. Schaafsma in 2014. This theory posits that the pressure wave generated by the heart is supported by a brief contraction of smooth muscle cells along the arterial tree.

Such a well-timed contraction would augment and distribute the pressure wave from the heart, enabling it to penetrate even the most remote capillary systems within the body. Since it is transient and occurs at stroke onset, it does not disrupt the ejection phase of the heart.

The theory of arterial acceleration represents an alternative to the theory of arterial stiffness formulated in the 19th century. It builds upon the work of Harvey (1628), who recognized the heart as the driving force behind blood circulation. If you are intrigued by how the theory of arterial acceleration contributes to the scientific pursuit of a deeper understanding of arterial blood pressure, please follow this link.

The theory of arterial acceleration has motivated the development of a model for cardiovascular simulation that can be downloaded from this website. This model has also led to a new approach for signal parameterization implemented in Compumedics DWL QL software for TCD machines. These parameters can be transformed to so-called Z-scores in order to correct for the normally occurring decrease in blood flow velocities with aging.

Combining the Z-scores for four different parameters enables doctors to interpret the TCD signal in complex clinical situations.

In 2022, Neuromon launched a new CardioVascularSimulation program, which is now available for MacOS on the AppStore.