These webpages have been created to guide users through all features of Neuromon's CardioVascular Simulation. The main aim of the model is to integrate physiological knowledge about cardiovascular function into a single computer entity. The model does not claim to fully mimic reality. Nevertheless, it allows the user to study possible interactions of patho-physiological changes and therapeutical interventions creating a higher level of understanding. New insights based on the model are, of course, hypothetical and require validation in real patient studies.
3. Calculating volume distribution over time
4. Implementing the Theory of Arterial Acceleration
6. Calculating CO2 concentrations or pressures
7. Metabolic response and auto regulation
8. Venous capacitance and cardiac output
9. Implementing the CNS Ischemic Response
10. Implementing the Bainbridge Response
11. Implementing the Baroceptor Reflex
12. Arterial Resistance and Capacitance
13. Changes in arterial biomechanics with aging
14. Menu options
15. Scenario options
16. Therapy options
18. Epilogue
In a recent update of Neuromon's CardioVascularSimulationApp (version 2.0 and higher) a simulation was added of the hypothetical collaboration of arterial acceleration and EDRF. It is generally believed that EDRF causes relaxation of distal arteries. But in order to do so, it is necessary that EDRF effectively reaches these arteries. Arterial acceleration hypothetically supports the spread of EDRF despite unfavourable tissue conditions
For a more detailed discussion (and simulation), see: What can be learned from arterial acceleration versus EDRF simulation?
